Comparative study between 3D-QSAR and Docking-Based Pharmacophore models for potent Plasomodium falciparum dihydroorotate dehydrogenase inhibitors

The pharmacophore mapped conformation of the test compound NO.65 (equal ensemble of A26) is well-overlapped with the A26 inhibitor of Pf DOHDH complex structure (PDB ID: 1TV5), rmsd = 0.475.286