Synthesis and activity of novel tetrazole compounds and their pyrazole-4-carbonitrile precursors against Leishmania spp

A series of 5-(1-aryl-3-methyl-1H-pyrazol-4-yl)-1H-tetrazole derivatives (4a-m) and their 1-aryl-3-methyl-1H-pyrazole-4-carbonitriles (3a-m) precursors were synthesized and evaluated for their antileishmanial activity.