Optimisation of a 5-[3-phenyl-(2-cyclic-ether)-methyl-ether]-4-aminopyrrolopyrimidine series of IGF-1R inhibitors

Optimisation of a 5-[3-phenyl-(2-cyclic-ether)-methyl-ether]-4-aminopyrrolopyrimidine series of IGF-1R inhibitors

Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 26, Issue 8, 15 April 2016, Pages 2057-2064

Robin A. Fairhurst, Thomas H. Marsilje, Stefan Stutz, Andreas Boos, Michel Niklaus, Bei Chen, Songchun Jiang, Wenshuo Lu, Pascal Furet, Clive McCarthy, Frédéric Stauffer, Vito Guagnano, Andrea Vaupel, Pierre-Yves Michellys, Christian Schnell,