Design, synthesis and biological evaluation of 2-mercapto-3-phenethylquinazoline bearing anilide fragments as potential antitumor agents: Molecular docking study

Compounds 15, 16 and 19 possessed the most remarkable broad-spectrum antitumor activities, additionally; compound 15 almost sevenfold more active than the known drug 5-FU with GI50 values of 3.16 and 22.60 μM, respectively.