Synthesis, stereochemistry and antimicrobial studies of novel oxime ethers of aza/diazabicycles

Two series of heterobicyclic oxime ethers viz, 3-ABN-9-one and 3,7-DABN-9-one O-benzyloximes were synthesized and stereochemistry was established by their spectral and crystal studies. All the synthesized oxime ethers were screened against a set of pathogenic bacteria and fungi. From the results, structure-activity relationship was discussed.