α-Chitin nanofibrils improve inflammatory and fibrosis responses in inflammatory bowel disease mice model

► Anti-inflammatory effects of α-chitin nanofibrils in acute ulcerative colitis. ► α-Chitin nanofibrils induced anti-inflammatory effects by suppressing NF-κ B. ► α-Chitin nanofibrils reduced monocyte chemotactic protein-1 concentrations. ► α-Chitin nanofibrils suppressed fibrosis.