QSAR studies on structurally similar 2-(4-methanesulfonylphenyl)pyran-4-ones as selective COX-2 inhibitors: a Hansch approach

QSAR analysis has been consummated on two recently reported novel series of 2,3-diaryl pyran derivatives with 2-(4-methanesulfonylphenyl)pyran-4-ones as a common template to discern the physicochemical and structural stipulations for selective COX-2 inhibition.