Keywords: Quercetin; Quercetin derivatives; Quercetin glycosides; Antioxidant activity; Anti-inflammatory activity; 12-HETE; 12(S)-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoic acid; 12-HHT; 12(S)-hydroxy(5Z,8E,10E)-heptadecatrienoic acid; 12-LOX; 12-lipoxygenase; AA; a
مقالات ISI (ترجمه نشده)
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Keywords: Mushroom; Anti-inflammatory activity; In vitro model; Animal model; Chemopreventive property; Therapeutic potential; CD; Crohn's disease; ConA; concanavalin A; COX-1; cyclooxygenase-1; COX-2; cyclooxygenase-2; DAI; disease activity index; DSS; dextran s
Keywords: COX-1; cyclooxigenase-1; COX-2; cyclooxigenase-2; NSAIDs; nonsteroidal antiinflammatory drugs; PG; prostaglandin; PGH2; prostaglandin G2; SAR; structure-activity relationships; QSAR; quantitative structure-activity relationships; ACHN; 1,1â²-azobis(cyano
Keywords: Antiplatelet; Preclinical studies; Structure-activity relationship (SAR) studies; Pharmacokinetic parameters; Safety profile; AA; arachidonic acid; ADP; adenosine diphosphate; ATP; adenosine triphosphate; CNS; central nervous system; COX-1; cyclooxygenase
Keywords: Aspirin-exacerbated respiratory disease (AERD); Asthma; Aspirin (acetylsalicylic acid, ASA); Chronic rhinosinusitis with nasal polyps; Nonsteroidal antiinflammatory drugs (NSAID); Hypersensitivity; Intolerance; AERD; aspirin-exacerbated respiratory diseas
Keywords: Cyclooxygenase; Tectorigenin; Isoflavones; Platelets; AA; arachidonic acid; ASA; acetylsalicylic acid; COX-1; cyclooxygenase-1; EDTA; ethylendiamintetraacetic acid; PRP; platelet rich plasma; PPP; platelet poor plasma; TXA2; thromboxane A2;
Keywords: ABPST; Brazilian Association of People with Thalidomide Syndrome; AKT; protein kinase B; bFGF; basic fibroblast growth factor; COX-1; cyclooxygenase-1; COX-2; cyclooxygenase-2; ENL; erythema nodosum of leprosy; eNOS; endothelial nitric oxide synthase; FLK
Keywords: GSH; glutathione; HSP-70; heat shock protein-70; SOD; superoxide dismutase; MDA; malondialdehyde; MPO; myeloperoxidase; TNF-α; tumor necrosis factor-α; IL-6; interleukin-6; EGF; epidermal growth factor; VEGF; vascular endothelial growth factor; COX-1; c
Anthocyanin supplementation in alleviating thrombogenesis in overweight and obese population: A randomized, double-blind, placebo-controlled study
Keywords: ACN/s; anthocyanin/s; APTT; activated partial thromboplastin time; ADP; adenosine diphosphate; PE-Cy7; allophycocyanin-cyanine 7; APC; allophycocyanin; ANOVA; analysis of variance; BMI; body mass index; CVD; cardiovascular disease; COX-1; cyclooxygenase-1
Keywords: NF-κB; nuclear factor kappa-light chain enhancement of activated B cell; NLR; (Nod)-like receptor; NLRP 3; (Nod)-like receptor pyrin domain containing 3 inflammasome; IL-1α; interleukin-1-alpha; IL-1β; interleukin-1-beta; IL-4; interleukin-4; IL-6; int
Keywords: AERD; CRS; CRSwNP; Asthma; Samter's disease; Sinus; AERD; aspirin-exacerbated respiratory disease; COX-1; cyclooxygenase 1; CRS; chronic rhinosinusitis; CRSwNP; chronic rhinosinusitis with nasal polyps; CRSwNPÂ + Asthma; chronic rhinosinusitis with nasal
Techniques for biological fingerprinting of traditional Chinese medicine
Keywords: Biological fingerprinting; Traditional Chinese medicine; Ultrafiltration; Cell membrane chromatography; Immobilized nanoparticles; Capillary electrophoresis; Adsorbed hollow fibers; Two-dimensional turbulent flow chromatography; BF; biological fingerprint
Keywords: Diabetes; Endothelial dysfunction; Endothelium-dependent hyperpolarization; Nitric oxide; Subcutaneous artery; NO; nitric oxide; EDH; endothelium-dependent hyperpolarization; eNOS; endothelial nitric oxide synthase; T2DM; type 2 diabetes mellitus; TRAM 34
Keywords: ADP; adenosine diphosphate; AACE; American Association of Clinical Endocrinologists; cox-1; cyclo-oxygenase-1; CVD; cardiovascular disease; EGIR; European Group for the study of Insulin Resistance definition; GP; Glycoprotein; HDL; high density lipoprotei
Keywords: ADP; adenosine diphosphate; ANOVA; analysis of variance; APC; allophycocyanin; aPTT; activated partial thromboplastin time; COX-1; cyclooxygenase-1; CVD; cardiovascular disease; C3GE; cyanidin-3-glucoside equivalents; FBC; full blood count; FITC; fluoresc
Keywords: Polyphenols; Herbs; Anise myrtle; Lemon myrtle; Tasmannia pepper leaf; COX-1; COX-2; iNOS
Keywords: COX-1; cyclooxygenase-1; AA; arachidonic acid; TXA2; thromboxane A2; acCOX-1; acetylated COX-1; nacCOX-1; non-acetylated COX-1; TXB2; thromboxane B2; PRP; Platelet rich plasma; VN Aspirin Assay; VerifyNow® Aspirin assay; PDP; Platelet depleted plasma; an
Keywords: Th1; type 1 T helper cells; Th2; type 2 T helper cells; CNS; central nervous system; BBB; blood-brain barrier; IL-2; interleukin-2; IL-12; interleukin-12; IL-10; interleukin-10; IL-4; interleukin-4; IL-6; interleukin-6; TNF-α; tumor necrosis factor a
Keywords: ADP; adenosine 5â²-diphosphate; AA; arachidonic acid; CLA; conjugated linoleic acid; COX-1; cyclooxygenase-1; CVD; cardiovascular disease; DHA; docosahexaenoic acid; EFSA; European Food Safety Authority; EPA; eicosapentaenoic acid; GP; glycoprotein; ICAM
Keywords: NO; nitric oxide; COX-1; cyclooxygenase-1; eNOS; endothelial nitric oxide synthase; CCl4; carbon tetrachloride; MAP; mmHg, mean arterial pressure; PP; mmHg, portal pressure; PBF; ml minâ1, portal blood flow; SMABF; ml minâ1, superior mesenteric arte
Design, synthesis, anti-inflammatory activity and molecular docking of potential novel antipyrine and pyrazolone analogs as cyclooxygenase enzyme (COX) inhibitors
Keywords: Synthesis; Antipyrine; Pyrazolone derivatives; COX-1; COX-2; Anti-inflammatory activity; Molecular modeling;
Characterization and optimization of phenolics extracts from Acacia species in relevance to their anti-inflammatory activity
Keywords: Acacia tortilis; Acacia farnesiana; Acacia longifolia; Phenolics; Anti-inflammatory activity; COX-1; COX-2;
The biological activities of roots and aerial parts of Alchemilla vulgaris L.
Keywords: AVA; Alchemilla vulgaris aerial parts methanolic extract; AVR; Alchemilla vulgaris roots methanolic extract; ROS; reactive oxygen species; COX-1; cyclooxygenase-1; COX-2; cyclooxygenase-2; PGH2; prostaglandin H2; NSAIDs; non-steroidal anti-inflammatory dr
Lipopolysaccharide (LPS)-mediated priming of toll-like receptor 4 enhances oxidant-induced prostaglandin E2 biosynthesis in primary murine macrophages
Keywords: ONS; oxidative/nitrosative stress; TLR; toll-like receptor; LPS-EK (Ultrapure); lipopolysaccharide from E. coli K12; TLR4-WT macrophages; macrophages derived from wild-type mice; TLR4-KO macrophages; macrophages derived from complete TLR4 knock-out mice;
Synthesis, biological evaluation and docking study of N-(2-(3,4,5-trimethoxybenzyl)benzoxazole-5-yl) benzamide derivatives as selective COX-2 inhibitor and anti-inflammatory agents
Keywords: N-(3,4,5-trimethoxybenzyl)benzoxazole; COX-1; COX-2; Anti-inflammatory activity; Ulcerogenic activity; Histopathology;
The colourless carotenoids phytoene and phytofluene: From dietary sources to their usefulness for the functional foods and nutricosmetics industries
Keywords: ABA; abscisic acid; ABTS; 2,2-azinobis-3-ethylbenzothiazoline-6-sulfonic acid; ARE; antioxidant response element; BCAR; β-carotene; BHT; butylated hydroxytoluene; CD; control diet; CD36; cluster of differentiation 36; c.d.b.; conjugated double bonds; COX
Angiotensin II Type 1a Receptors in the Subfornical Organ Modulate Neuroinflammation in the Hypothalamic Paraventricular Nucleus in Heart Failure Rats
Keywords: AAV; adeno-associated virus; ACE; angiotensin converting enzyme; AT1R; angiotensin II type 1 receptors; AT1aR; angiotensin II type 1a receptors; AngII; angiotensin II; AVP; arginine vasopressin; BW; body weight; CD68; cluster of differentiation 68; CL; le
The dichotomous role of H2S in cancer cell biology? Déjà vu all over again
Keywords: 1400 W; N-[[3-(aminomethyl)phenyl]methyl]-ethanimidamide; 3-MP; 3-Mercaptopyruvate; 3-MST; 3-Mercaptopyruvate sulfurtransferase; ADT-OH; 5-(4-hydroxyphenyl)-3H-1, 2-dithiole-3-thione; AG; Aminoguanidine; AOAA; Aminooxyacetic acid; CAT; Cysteine aminotra
Design, synthesis, anti-inflammatory antitumor activities, molecular modeling and molecular dynamics simulations of potential naprosyn® analogs as COX-1 and/or COX-2 inhibitors
Keywords: Synthesis; Naprosyn analogs; COX-1; COX-2; Anti-inflammatory activity; Antitumor screening; Docking studies; Dynamic simulations study; NCI cancer screening;
Phytotoxic activity of diclofenac: Evaluation using a model green alga Chlamydomonas reinhardtii with atrazine as a reference substance
Keywords: Diclofenac; Atrazine; Phytotoxicity; Chlamydomonas; Chlorophyll fluorescence in vivo; Oxidative stress; ABS/RC; absorption flux per reaction center; APX; ascorbate peroxidase; AT; atrazine; CAT; catalase; CECs; contaminants of emerging concern; COX-1; cy
Selection of P2Y12 Inhibitor in Percutaneous Coronary Intervention and/or Acute Coronary Syndrome
Keywords: ACS; acute coronary syndrome; ACCOAST trial; Comparison of Prasugrel at the Time of Percutaneous Coronary Intervention or as Pretreatment at the Time of Diagnosis in Patients with Non-ST Elevation Myocardial Infarction trial; ACUITY; acute catheterization
Astaxanthin: A mechanistic review on its biological activities and health benefits
Keywords: Astaxanthin (PubChem CID: 5368397); Beta-Carotene (PubChem CID: 5280489); Beta-Cryptoxanthin (PubChem CID: 5281235); Canthaxanthin (PubChem CID: 5281227); Lutein (PubChem CID: 5281243); Zeaxanthin (PubChem CID: 5280899); Alpha-Tocopherol (PubChem CID: 149
Melatonin therapy for diabetic cardiomyopathy: A mechanism involving Syk-mitochondrial complex I-SERCA pathway
Keywords: Melatonin; SERCA; COX-1; Syk; Diabetic cardiomyopathy;
Effect of acetylcholinesterase inhibitors donepezil and rivastigmine on the activity and expression of cyclooxygenases in a model of the inflammatory action of fluoride on macrophages obtained from THP-1 monocytes
Keywords: ROS; reactive oxygen species; COX; cyclooxygenases; COX-1; cyclooxygenase 1; COX-2; cyclooxygenase 2; D; donepezil; R; rivastigmine; Ptgs1; prostaglandin G/H synthase 1 gene; Ptgs2; prostaglandin G/H synthase 2 gene; Cyclooxygenase; Fluoride; Rivastigmine
1,2,3-triazole tethered Indole-3-glyoxamide derivatives as multiple inhibitors of 5-LOX, COX-2 & tubulin: Their anti-proliferative & anti-inflammatory activity
Keywords: Indole-3-glyoxamide derivatives; 1,2,3-triazoles; COX-1; COX-2; 5-LOX; Tubulin; Anti-proliferation;
Design & synthesis of novel oxazolone & triazinone derivatives and their biological evaluation as COX-2 inhibitors
Keywords: Oxazolone; Triazinone; COX-1; COX-2; Synthesis; Anti-inflammatory; Antitumor;
Prostaglandin D2 is the major cyclooxygenase-1-derived product in prepartum mouse uteri where it mediates an enhanced in vitro myometrial contraction
Keywords: COX-1; Prostaglandin; Prepartum; Myometrial contraction;
First record of Gongylonema nepalensis in domestic and wild ruminants in Europe
Keywords: Gongylonema nepalensis; Ruminant; Sardinia island; Scanning electron microscopy; rDNA; cox-1; New geographical record; New host record;
Chronic administration of saturated fats and fructose differently affect SREBP activity resulting in different modulation of Nrf2 and Nlrp3 inflammasome pathways in mice liver
Keywords: ACC; acetyl CoA carboxylase; ApoB; apolipoprotein B; COX-1; cytochrome c oxidase subunit 1; CPT1-l; carnitine palmitoyltrasnferase; FAS; fatty acid synthase; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; GCLC; glutamate-cysteine ligase catalytic; GCL
Bletilla striata: Medicinal uses, phytochemistry and pharmacological activities
Keywords: α-SMA; alpha smooth muscle actin; ABTS, 2; 2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid); ADP; adenosine diphosphate; BSP; Bletilla striata polysaccharides; CFDA; China Food and Drug Administration; Con A; concanavalin A; COX-1; cyclooxygenase-1;
Introduction of β-d-mannuronic acid (M2000) as a novel NSAID with immunosuppressive property based on COX-1/COX-2 activity and gene expression
Keywords: ANOVA; analysis of variance; AA; arachidonic acid; BUN; blood urea nitrogen; COX; cyclooxygenase; EAE; experimental autoimmune encephalomyelitis; IRAK1; interleukin-1 receptor-associated kinase 1; LPS; lipopolysaccharide; LPS-EB; LPS from E. coli O111: B4
Dexibuprofen prevents neurodegeneration and cognitive decline in APPswe/PS1dE9 through multiple signaling pathways
Keywords: AD; Alzheimer's disease; Aβ; Amyloid beta; APP; Amyloid precursor protein; NFTs; Neurofibrillary tangles; BACE1; β-secretase 1; TNF-α; Tumor necrosis factor; iNOS; Inducible nitric oxide synthase; NSAIDs; Non-steroidal anti-inflammatory drugs; PPARγ;
Lipidomics in translational research and the clinical significance of lipid-based biomarkers
Keywords: 5-HETE; 5-hydroxyicosatetraenoic acid; 12-HETE; 12-hydroxyicosatetraenoic acid; 15-HETE; 15-hydroxyicosatetraenoic acid; aa; diacyl; ae; acyl-alkyl; ACs; acylcarnitines; ACOG; The American College of Obstetricians and Gynecologists; AD; Alzheimer's dise
First report of Metastrongylus pudendotectus by the genetic characterization of mitochondria genome of cox1 in pigs from Tibet, China
Keywords: Metastrongylus pudendotectus; Tibetan pigs; Lung worm; Cox-1; Genetic characterization
The expression of prostaglandin-E2 and its receptor in the oviduct of Chinese brown frog (Rana dybowskii)
Keywords: COX-1; COX-2; PGE2; EP4; Oviduct; Rana dybowskii
Simultaneous quantification of PGI2 and TXA2 metabolites in plasma and urine in NO-deficient mice by a novel UHPLC/MS/MS method
Keywords: PGI2; prostacyclin; TXA2; thromboxane A2; IP; PGI receptor; TP; TX receptor; PLA2; phospholipase A2; PGIS; prostacyclin synthase; TXS; thromboxane A synthase; UHPLC/MS/MS; ultra high-performance liquid chromatography coupled to mass spectrometry; TXB2; th
Efficacy and safety of Derris scandens (Roxb.) Benth. for musculoskeletal pain treatment: A systematic review and meta-analysis of randomized controlled trials
Keywords: NLEMs; National List of Essential Medicines; NSAIDs; Nonsteroidal anti-inflammatory drugs (NSAIDs); COX-1; Cyclooxygenase 1; LTB4; Leukotriene-B4; AEs; Adverse events; RCT; Randomized controlled trial; PRISMA; Preferred Reporting Items for Systematic Revi
Comparative study of biological activities and phytochemical composition of two rose hips and their preserves: Rosa canina L. and Rosa arvensis Huds.
Keywords: 12-HETE; 12(S)-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoic acid; 12-HHT; 12(S)-hydroxy(5Z,8E,10E)-heptadecatrienoic acid; 12-LOX; 12-lipoxygenase; AAE; ascorbic acid equivalents; BHT; butylated hydroxytoluene; COX-1; cyclooxygenase-1; DPPH; 2,2-diphenyl-1-pi
Enhancing T cell therapy by overcoming the immunosuppressive tumor microenvironment
Keywords: ACT; adoptive T cell therapy; TLS; tertiary lymphoid structures; MDSC; myeloid derived-supressor cells; Tfh; T follicular helper; NSCLC; non-small cell lung cancer; MSR; mesoporous silica rods; PSC; pancreatic stellate cells; TIL; tumor-infiltrating lymph
In vitro and in vivo assessment of meadowsweet (Filipendula ulmaria) as anti-inflammatory agent
Keywords: FUA; F. ulmaria aerial part extract; FUR; F. ulmaria root extract; COX-1; cyclooxygenase-1; COX-2; cyclooxygenase-2; LOX; lipoxygenase; NSAIDs; nonsteroidal anti-inflammatory drugs; HPTLC; high performance thin layer chromatography; HPLC; high performance