Evaluation of tropicamide-loaded tamarind seed xyloglucan nanoaggregates for ophthalmic delivery

► Preparation of tamarind seed xyloglucan nanoaggregates. ► Optimization of tropicamide-loaded TSX nanoaggregates using face centred design. ► Corneal permeation characteristics of tropicamide-loaded TSX nanoaggregates. ► Ocular tolerance of tropicamide-loaded TSX nanoaggregates. ► Biocompatibility of tropicamide-loaded TSX nanoaggregates.