Dual stimuli-responsive N-phthaloylchitosan-graft-(poly(N-isopropylacrylamide)-block-poly(acrylic acid)) copolymer prepared via RAFT polymerization

► N-Phthaloylchitosan-g-(NIPAAm-b-PAA) graft copolymer was synthesized via RAFT. ► The chain transfer agent was obtained by modification of chitosan with BPATT. ► The graft copolymer could assemble to micelles in aqueous solution. ► Thermo-responsive behaviors can be tuned by the formation of branch chain and pH.