Scutellarin-cyclodextrin conjugates: Synthesis, characterization and anticancer activity

► Three scutellarin-β-cyclodextrin conjugates were prepared and confirmed. ► XRD and TG spectrometry characterized these conjugates. ► The aqueous solubility of the conjugates was much higher than that of scutellarin. ► The conjugates could hardly be hydrolyzed to scutellarin in aqueous solutions. ► The anti-colon cancer activities of the conjugates were better than that of scutellarin.