کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10602347 982374 2011 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Screening on the immune-enhancing active site of Siberian solomonseal rhizome polysaccharide
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Screening on the immune-enhancing active site of Siberian solomonseal rhizome polysaccharide
چکیده انگلیسی
The total Siberian solomonseal rhizome polysaccharide (SRPSt) and four fractional SRPS30, SRPS50, SRPS70 and SRPS80, were extracted by one-step or stepwise ethanol precipitation method. In test in vitro, their effects on chicken peripheral lymphocytes proliferation were compared. The result showed that SRPS70 and SRPS50 presented better effect. In test in vivo, 14-day-old chickens were injected, respectively, with SRPS50, SRPS70 and SRPSt, at the first vaccination of ND vaccine, once a day for three successive days. On days 7, 14, 21 and 28 after the first vaccination, the peripheral lymphocytes proliferation and antibody titer were determined. The result indicated that lymphocyte proliferation and antibody titers in SRPS50 group at all time points were the highest, significantly higher than those of non-adjuvant control group and most of another two SRPSs groups. These results confirmed that SRPS50 possessed the strongest action and was the immune-enhancing active site of SRPS.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Carbohydrate Polymers - Volume 85, Issue 3, 1 June 2011, Pages 687-691
نویسندگان
, , , , , , , , ,