کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10602595 | 982388 | 2011 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
A biodegradable in situ injectable hydrogel based on chitosan and oxidized hyaluronic acid for tissue engineering applications
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: A biodegradable in situ injectable hydrogel based on chitosan and oxidized hyaluronic acid for tissue engineering applications A biodegradable in situ injectable hydrogel based on chitosan and oxidized hyaluronic acid for tissue engineering applications](/preview/png/10602595.png)
چکیده انگلیسی
An “in situ” biodegradable gel consisting of chitosan, glycerol phosphate (GP) and oxidized hyaluronic acid (HDA) were synthesised and characterized .This is a two component hydrogel system where chitosan neutralized with GP resulted in instantaneous gelling when combined with HDA. The gels are cytocompatible and could be freeze dried to form porous scaffolds. The percentage porosity of the freeze-dried chitosan hyaluronic acid dialdehyde gels (CHDA) increased with increasing oxidation. Fibroblast cells seeded onto CHDA porous scaffolds adhered, proliferated and produced ECM components on the scaffold. Chondrocytes encapsulated in CHDA gels retained their viability and specific phenotypic characteristics. The gel material is hence proposed as a scaffold and encapsulating material for tissue engineering applications.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Carbohydrate Polymers - Volume 85, Issue 4, 1 July 2011, Pages 838-844
Journal: Carbohydrate Polymers - Volume 85, Issue 4, 1 July 2011, Pages 838-844
نویسندگان
Sandhya Nair, N.S. Remya, S. Remya, Prabha D. Nair,