In situ forming polysaccharide-based 3D-hydrogels for cell delivery in regenerative medicine

► In situ forming polysaccharide-based gels for cell delivery in regenerative medicine. ► Chemically cross-linked with natural product derivatives to reduce toxicity. ► Thermosensitive hydrogels of polysaccharides designed to gel at body temperature. ► Composite hydrogels allow adhesion and expansion of anchorage-dependent cells. ► Reversible shear-responsive gels are 3D structures with tunable mechanical properties.