Superior disintegrating properties of calcium cross-linked Cassia fistula gum derivatives for fast dissolving tablets

► Cassia fistula gum derivatives evaluated for superior disintegrating potential in FDTs. ► Superior disintegration achieved due to decreased WST and particle density. ► Mechanism involved enhanced SI, Reff.p and particle volume. ► CaCOG (5%, w/w) displayed better performance compared to CaCEG (5%, w/w).