Thiolated pectin nanoparticles: Preparation, characterization and ex vivo corneal permeation study

► Thiolated pectin nanoparticles prepared by ionotropic gelation using MgCl2. ► Nanoparticles size increased with increase in magnesium chloride concentration. ► Decrease in % drug entrapment with increase in thiolated pectin concentration. ► Higher corneal permeation from nanoparticle formulation than conventional formulation.