Antioxidant properties of yeast (1→3)-β-d-glucan studied by electron paramagnetic resonance spectroscopy and its activity in the adjuvant arthritis

In the in vivo experiments involving administration of CMG to rats with experimentally induced adjuvant arthritis (AA) a substantial decline of the level of plasmatic carbonyls, a parameter indicating oxidative tissue damage during the progress of arthritic diseases, was observed. We assume that radical-scavenging properties of CMG can be responsible for its antioxidant activity in the AA model, suggesting possible application of the yeast glucan derivatives in the treatment of arthritis.