Chitosan microcapsules loaded with either miconazole nitrate or clotrimazole, prepared via emulsion technique

► Two chitosan microcapsules loaded with different antifungal agents were prepared. ► Different drug loadings were prepared by ultrasound-assisted o/w emulsion method. ► Chitosan/miconazole nitrate microcapsules release ∼49.5% of the drug after 12 h. ► Chitosan/clotrimazole microcapsules release ∼66.1% of the drug after 12 h. ► Patients with tinea pedis can undergo medical treatment by putting on these socks.