Chitosan-functionalized poly(methyl methacrylate) particles by spinning disk processing for lipase immobilization

► Chitosan-decorated polymer particles were prepared via spinning disk processing. ► Processing parameters were fine-tuned to obtain the optimum condition. ► Molecular weights of chitosan can affect size and surface charge of the particles. ► Lipase can be electrostatically immobilized on chitosan-decorated particles. ► Activity of immobilized lipase can be preserved and increased with lipase loading.