Response surface methodology for optimization of the ultrasonic extraction of polysaccharides from Codonopsis pilosula Nannf.var.modesta L.T.Shen

The experimental data were fitted to a second-order polynomial equation using multiple regression analysis and also examined using the appropriate statistical methods. The best extraction conditions are as follows: extraction time 44 min, ratio of water to raw material 56 and ultrasonic power 320 W. Under the optimization conditions, the experimental yield was 36.264%, which was well matched with the predictive yield.