Synthesis of glycolipopeptidic building blocks for carbohydrate receptor discovery

► Glycolipopeptidic building blocks for the dynamic combinatorial library. ► A new tool in the glycotherapeutics development. ► Lipoamino acids convert glycopeptides into amphiphiles. ► Amphiphiles interact non-covalently and form micelles in a dynamic self-assembly. ► Micelles for screening to identify carbohydrate ligands.