کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10624753 | 989606 | 2015 | 54 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Gel casting of hydroxyapatite with naphthalene as pore former
ترجمه فارسی عنوان
ریخته گری هیدروکسی آپاتیت با نفتالین به عنوان منافذ سابق
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی مواد
سرامیک و کامپوزیت
چکیده انگلیسی
The present study discusses the processing and characterization of HA scaffolds which have been processed through a combination of gel casting and fugitive addition. The additional use of Napthalene (NA) as fugitive in the gel casting process provides an additional parameter for tailoring the porosity over and above that obtained through gel casting route. The motive behind the use of combination process was to prepare a porous hydroxyapatite (HA) scaffold with wide porosity range along with sufficient mechanical strength. In house prepared HA powder was used as the staring powder and Methyl acrylamide - N,Nâ²-Methylene-bis-acrylamide (MAM-MBM) system was used for gel casting. Varying amount of Naphthalene (10-40Â vol%) and HA solid loading (27-54Â vol%) were used for scaffold preparation. The maximum solid loading that could be casted was 48Â vol%. The sintered porous Hydroxyapatite-Naphthalene (HA-NA) scaffolds had been characterized for phase stability, microstructure, pore size and pore morphology. The highest compressive strength was 7.51Â MPa recorded for 22% porosity samples, and it was 0.75Â MPa for 81% porosity samples. Scaffolds prepared with lower solid loading had good pore interconnectivity. In vitro bioactivity study of the scaffolds showed dissolution of scaffold up to 3 weeks in SBF solution followed by deposition of calcium phosphate as apatite layer. MTT assay results showed acceptable limit of cell growth and proliferation.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Ceramics International - Volume 41, Issue 3, Part A, April 2015, Pages 3775-3790
Journal: Ceramics International - Volume 41, Issue 3, Part A, April 2015, Pages 3775-3790
نویسندگان
Smruti Rekha Dash, Ritwik Sarkar, Santanu Bhattacharyya,