Synthesis, characterisation and in vitro evaluation of sol-gel derived SiO2-P2O5-CaO-B2O3 bioactive system

The bioactivity of the samples has been analysed in vitro in simulated body fluid (SBF). The evolution of apatite layers self-assembled on the samples surface after immersion in SBF was analysed and discussed as a function of both boron content and immersion time. The results indicate that after five days of immersion, the microstructure of the sample with 10 mol% B2O3 is quite close to that of dry human trabecular bone.