During the stationary growth phase, Yarrowia lipolytica prevents the overproduction of reactive oxygen species by activating an uncoupled mitochondrial respiratory pathway

► Interactions of orthodox and alternative respiratory enzymes are dynamic. ► Association/dissociation of respiratory enzymes modulates electron pathways. ► Pathways condition coupling and control ROS production. ► In the stat-phase an uncoupled alternative pathway is activated. ► In the stat-phase, NDH2e increases while complex IV decreases.