Integrin-associated protein (CD47) is a putative mediator for soluble fibrinogen interaction with human red blood cells membrane

► We studied soluble fibrinogen interaction with human erythrocyte membrane. ► Fibrinogen-erythrocyte interaction is integrin-like receptor independent. ► This interaction is erythrocyte age-dependent. ► CD47 is a mediator of the soluble fibrinogen binding to human erythrocyte membrane.