Molecular organization of antibiotic amphotericin B in dipalmitoylphosphatidylcholine monolayers induced by K+ and Na+ ions: The Langmuir technique study

► K+ and Na+ ions play an important role in molecular organization of AmB in DPPC monolayers. ► The results proved a high affinity of AmB towards DPPC induced by the presence of K+ than Na+ ions. ► The stoichiometry of the most stable AmB and DPPC monolayers was 1:1 and 2:1 in presence of K+ and Na+ ions.