Conformational changes of β2-human glycoprotein I and lipid order in lipid-protein complexes

► Beta2 human glycoprotein I-anionic lipid complexes were studied by infrared spectroscopy. ► The proportion of alpha helix increased in the lipid-bound protein. ► The lipid order increased in the lipid-protein complexes. ► Complexes were disrupted when the protein was unfolded by increasing the temperature.