Yeast and human RNA helicases involved in ribosome biogenesis: Current status and perspectives

► We review on yeast and human RNA helicases involved in ribosome biogenesis. ► We discuss on the dynamics of yeast RNA helicases during ribosome synthesis. ► We describe the molecular roles of these enzymes and discuss on their cofactors. ► We describe the role of human RNA helicases involved in ribosome synthesis. ► We discuss on the future challenges for the research on these enzymes.