Dbp5 - From nuclear export to translation

► The DEAD-box RNA helicase Dbp5 is an essential and conserved mRNA export factor. ► Dbp5 functions in the ATP dependent remodeling of RNA/protein complexes. ► Dbp5 requires the nucleoporin Nup159 and its cofactors Gle1 and IP6 for its activity. ► Dbp5 has an additional function in translation termination.