KSRP silencing favors neural differentiation of P19 teratocarcinoma cells

► KSRP function is required to keep teratocarcinoma P19 cells in an undifferentiated state. ► KSRP favors the expression of two master regulators of neural differentiation. ► KSRP promotes the maturation of miR-200 family members from precursors. ► Maturation of miR-200 family members is reduced during P19 cell neural differentiation. ► KSRP silencing in P19 cells promotes the reshaping of their transcriptome.