T-2 toxin induces the expression of porcine CYP3A22 via the upregulation of the transcription factor, NF-Y

Although porcine CYP3A22 is homologous to hCYP3A4, the regulation of basal and induced expression of CYP3A22 occurred via distinct mechanisms. This may account for the variety of CYP3A expression in animals and humans.