Glutathione peroxidases

► Novel functions of GPx1-8 regarding the essential physiological functions of ROS ► Balancing levels of H2O2 in, e.g., insulin signalling by GPx1 ► The role of GPx2 in cancer depends on the mode of initiation and cancer stage ► Specific roles of GPx4 in apoptosis and together with GPx5 in male fertility ► Downregulation as well as overexpression of GPxs can have harmful effects.