Magnolol attenuates neointima formation by inducing cell cycle arrest via inhibition of ERK1/2 and NF-κB activation in vascular smooth muscle cells

► Magnolol was isolated from Magnoliae Cortex using column chromatography. ► Magnolol inhibited neo-intima formation in vivo. ► Magnolol induced cell cycle arrest at G0/G1 phase. ► Proliferation of VSMCs was ERK1/2 and NF-κB dependent.