Chaperoning steroidal physiology: Lessons from mouse genetic models of Hsp90 and its cochaperones

► The roles of Hsp90 and select cochaperones in steroidal physiology are reviewed. ► Mouse genetic models of Hsp90, p23, FKBP51, FKBP52 and PP5 are described in detail. ► Effects on glucocorticoid, androgen, and progesterone physiology have been found.