Store-operated Ca2Â + entry in proliferating and retinoic acid-differentiated N- and S-type neuroblastoma cells

► SOCE is down-regulated in differentiated N-type cells. ► STIM1 and Orai1 expression is down-regulated in differentiated N-type cells. ► TRPC1 expression is up-regulated in differentiated N-type cells. ► SOCE proteins could provide a therapeutic target in the treatment of neuroblastoma.