Hydroxylamine acutely activates glucose uptake in L929 fibroblast cells

► Hydroxylamine activates glucose uptake in L929 fibroblast cells within minutes. ► Actions of hydroxylamine are virtually identical to actions of nitroxyl. ► Activation by hydroxylamine is blocked by thiol-reactive compounds. ► Azide, a peroxidase inhibitor, blocks activating effects of hydroxylamine.