کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10815332 1058468 2013 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Aberrant association between vascular endothelial growth factor receptor-2 and VE-cadherin in response to vascular endothelial growth factor-a in Shb-deficient lung endothelial cells
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
پیش نمایش صفحه اول مقاله
Aberrant association between vascular endothelial growth factor receptor-2 and VE-cadherin in response to vascular endothelial growth factor-a in Shb-deficient lung endothelial cells
چکیده انگلیسی
► The abnormal Shb knockout mouse vascular permeability was currently investigated. ► Shb knockout endothelial cells showed reduced VEGF-A stimulated migration. ► Abnormal VEGFR-2 and VE-cadherin co-localization was noted in Shb knockout cells. ► This may partly be explained by reduced VEGF-A stimulated ERK/Akt/Rac1 activity. ► The findings increase our knowledge of mechanisms regulating vascular permeability.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Cellular Signalling - Volume 25, Issue 1, January 2013, Pages 85-92
نویسندگان
, , , , , , , , ,