Autophagy in regulation of Toll-like receptor signaling

► The expanded knowledge regarding TLR signaling is definitely summarized. ► Implications of ubiquitin-dependent signaling in TLR signaling are interpreted. ► General processes of autophagy, xenophagy and aggrephagy are definitely summarized. ► Effects of autophagy on TLR signaling are appropriately summarized. ► The crosstalk between TLR signaling and autophagy signaling is interpreted.