Regulation of C/EBPβ and resulting functions in cells of the monocytic lineage

► C/EBPβ isoforms may be involved in the development of monocytic lineage cells. ► LAP*/LAP inhibit proliferation and regulate differentiation-associated genes. ► C/EBPβ is involved in orchestrating the innate immune response. ► C/EBPβ dysregulation is involved in inflammatory disease, infection, and leukemia.