کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10822702 | 1061697 | 2005 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Structural biology of the thioester-dependent degradation and synthesis of fatty acids
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موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شیمی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Structural biology of the thioester-dependent degradation and synthesis of fatty acids Structural biology of the thioester-dependent degradation and synthesis of fatty acids](/preview/png/10822702.png)
چکیده انگلیسی
The fatty acid degradation and synthesis pathways consist of the same four chemical transformations. These transformations are facilitated by conjugating the fatty acid, via a thioester bond, to coenzyme A or acyl carrier protein in, respectively, the degradation and synthesis pathways. These pathways are compartmentalized in the peroxisomes, mitochondria and cytosol of eukaryotic cells. Current structural knowledge of the enzymes comprising these pathways shows that the approximately 130 entries in the RCSB Protein Data Bank can be grouped into seven superfamilies. Multifunctional enzymes are important in both pathways.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Current Opinion in Structural Biology - Volume 15, Issue 6, December 2005, Pages 621-628
Journal: Current Opinion in Structural Biology - Volume 15, Issue 6, December 2005, Pages 621-628
نویسندگان
Prasenjit Bhaumik, M Kristian Koski, Tuomo Glumoff, J Kalervo Hiltunen, Rik K Wierenga,