کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10823626 1061912 2005 15 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Error-prone DNA repair and translesion DNA synthesis
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شیمی
پیش نمایش صفحه اول مقاله
Error-prone DNA repair and translesion DNA synthesis
چکیده انگلیسی
Evelyn Witkin hypothesized in 1967 that bacterial cell division is controlled by a repressor which, like the lambda repressor, is inactivated by a complex process that starts with the presence of replication-blocking lesions in the DNA. She further suggested that this might not be the only cellular function to show induction by DNA damage. Three years later, Miroslav Radman, in a privately circulated note, proposed that one such function might be an inaccurate (mutation-prone) DNA polymerase under the control of the recA and lexA genes. Thus was born the SOS hypothesis.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: DNA Repair - Volume 4, Issue 6, 8 June 2005, Pages 725-739
نویسندگان
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