کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1082513 950949 2010 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Influence of trial registration on reporting quality of randomized trials: Study from highest ranked journals
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی سیاست های بهداشت و سلامت عمومی
پیش نمایش صفحه اول مقاله
Influence of trial registration on reporting quality of randomized trials: Study from highest ranked journals
چکیده انگلیسی

ObjectiveTo evaluate the reporting quality of key methodological items of randomized control trials (RCTs) in 55 of the highest ranked journals.Study Design and SettingA list of the highest top ranked journals was identified, and a search for detecting RCTs in those journals was made. Two hundred sixty four journals were screened and 55 of them were identified having at least one RCT. Three RCTs were randomly selected a priori from each journal; 148 RCTs were finally included. RCTs were assessed by two reviewers using the Consolidated Standards of Reporting Trials (CONSORT) statement.ResultsOnly 11 (8%) RCTs had all items adequately reported. In addition, 36% of RCTs reported that the study was registered in any trial registry. We found a significant difference in the quality of reporting for baseline characteristics, recruitment, participant's flow, and randomization implementation between those studies having reported the registration of their RCT in a trial registry and those that have not. Adherence to key methodological items of the CONSORT statement was as follows: sample size determination (60%), sequence generation (49%), allocation concealment (40%), and blinding (25%).ConclusionsReporting of varied CONSORT items remains suboptimal. Registration in a trial registry was associated with improved reporting. Further efforts to enhance RCT registration could contribute to this improvement.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Clinical Epidemiology - Volume 63, Issue 11, November 2010, Pages 1216–1222
نویسندگان
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