Pazopanib, a multitargeted tyrosine kinase inhibitor, reduces diabetic retinal vascular leukostasis and leakage

► Pazopanib reduced retinal leukostasis by 32% in STZ-induced rodent model of DR. ► Pazopanib reduced retinal vascular leakage by 39% in the above animal model. ► Pazopanib suspension eye drops can potentially alleviate complications of DR.