Retinal transfer of nicotinate by H+-monocarboxylate transporter at the inner blood-retinal barrier

► Nicotinic acid is a constituent of the coenzymes NAD and NADP. ► Nicotinic acid is widely used at high doses as a lipid-lowering drug. ► We examined nicotinate transport to the retina across the inner BRB. ► Nicotinate transport to the retina is mediated by MCTs at the inner BRB. ► Information will assist in the design of a suitable nicotinate dosage regimen.