Characterization and comparison of embryonic stem cell-derived KDRÂ + cells with endothelial cells

► We owned a hESC bank that contains about 300 hESC lines. ► KDR + cells were induced from hESC lines and their biological characteristics were analyzed. ► hESC derived KDR + cells were compared with both cord blood EPCs and HUVECs in vitro. ► Isolated embryonic KDR + cells (EC-KDR +) display characteristics that were similar to EPCs and HUVECs. ► After in vitro culture, EC-KDR + cells can differentiate into mature endothelial cells.