The antiangiogenic effects of levosimendan in a CAM assay

► We investigated effects of Levosimendan on angiogenesis. ► Chick embryo chorioallantoic membrane model was used. ► Levosimendan showed anti-angiogenic effect at 1 and 10 μmol/L concentrations. ► The antiangiogenic efficacy of levosimendan was comparable with that of Bevacizumab.