Impaired microvascular flow motion in subclinical diabetic feet with sudomotor dysfunction

► The pathophysiological basis underlying skin microcirculatory changes in subclinical diabetic feet. ► Impaired low-frequency flow motion correlated with sudomotor dysfunction. ► Vasomotion changes were mainly in neurogenic and endothelial components. ► Impaired systemic vascular tone was proportional to the degree of myogenic dysregulation.