Blood flow resistance in lesion vessels and normal host vessels evaluated by pulsed Doppler ultrasound

► Blood flow resistance (BFR) in the microcirculation was studied by pulsed Doppler ultrasound using thyroid as a model. ► Most of the BFR parameters were higher in malignant lesion vessels and lower in normal host vessels. ► Pulsed Doppler ultrasound can reflect the homogeneity condition of the distribution of BFR within a lesion. ► Low to moderate significant positive correlations of BFR between benign vessels and host vessels were found. ► Low negative correlations between the malignant nodule sizes and some of the BFR parameters were revealed.