کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1083103 950983 2011 12 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
GRADE guidelines: 1. Introduction—GRADE evidence profiles and summary of findings tables
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی سیاست های بهداشت و سلامت عمومی
پیش نمایش صفحه اول مقاله
GRADE guidelines: 1. Introduction—GRADE evidence profiles and summary of findings tables
چکیده انگلیسی

This article is the first of a series providing guidance for use of the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system of rating quality of evidence and grading strength of recommendations in systematic reviews, health technology assessments (HTAs), and clinical practice guidelines addressing alternative management options. The GRADE process begins with asking an explicit question, including specification of all important outcomes. After the evidence is collected and summarized, GRADE provides explicit criteria for rating the quality of evidence that include study design, risk of bias, imprecision, inconsistency, indirectness, and magnitude of effect.Recommendations are characterized as strong or weak (alternative terms conditional or discretionary) according to the quality of the supporting evidence and the balance between desirable and undesirable consequences of the alternative management options. GRADE suggests summarizing evidence in succinct, transparent, and informative summary of findings tables that show the quality of evidence and the magnitude of relative and absolute effects for each important outcome and/or as evidence profiles that provide, in addition, detailed information about the reason for the quality of evidence rating.Subsequent articles in this series will address GRADE’s approach to formulating questions, assessing quality of evidence, and developing recommendations.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Clinical Epidemiology - Volume 64, Issue 4, April 2011, Pages 383–394
نویسندگان
, , , , , , , , , , , , , , ,