Minimal disease activity in Gaucher disease: Criteria for definition

► Gaucher disease is the first lysosomal disease for which therapy became available. ► Gaucher patients with high disease burden are unlikely to achieve remission. ► Attaining reasonably good clinical status is realistic treatment goal for them. ► The Authors design the concept of minimal disease activity in Gaucher disease. ► Patients with minimal disease activity could be addressed to maintenance therapy.